Typical fatty acids cannot be converted to glucose because their catabolic pathways produce acetyl-CoA. It is a 2 carbon molecule, that is why it cannot be formed back into glucose. End product of glycolysis is a pyruvate molecule. Then, it is converted into acetyl-CoA by an enzyme. There are no available enzyme to be able to reverse this process and Acetyl CoA cannot participate in gluconeogenesis.
Typical fatty acids cannot be converted to glucose because ______________.