Biology
hollywood9
2016-04-30 20:04:57
How might a substrate of the citric acid cycle block respiration when it is present in great excess
ANSWERS
Julz418
2016-04-30 21:53:49

The substrate of the citric acid cycle which can block respiration when it is present in excess is MALONATE. Malonate inhibits respiration by competing with succinate dehydrogenase for its acitve site. Malonate binds to the active site without reacting, thus competing with succinate. This disrupts the cellular respiration in the cell.

ADD ANSWER